PReS-FINAL-2293: An attempt to analyze variants of systemic lupus erythematosus onsets in childhood

According to time from first manifestation to complete clinical presentation «Acute» onset: time from first symptom to complete clinical presentation is less than 1 month 9% (14 of 27) Among such cases were 4 (14,8%) with delayed (5-14 months) new organ involvement. 3 patients presented with renal involvement: 2 cases of microhematuria, proteinuria in patients without cytostatic therapy; 1 case of nephrotic syndrome in patient treated by chloroquine. 2 patients (treated by cytostatic drugs) presented with neuropsychiatric manifestations: seizures, focal cortical neurologic signs. «Subacute» onset: time from first symptom to complete clinical presentation from 1 to 3 months 14,8% (4 of 27). This variant is characterized by progressive, step-bystep involvement of new organ systems without any regularity in priority. «Prolonged» onset: slow evolution of clinical manifestations (from 8 to 24 months in this research) 33,3% (9 of 27)